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Central European Annals of Clinical Research

(ISSN: 2668-7305) Open Access Journal
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Central European Annals of Clinical Research (CEACR) is no longer published on JAMS (the publishing platform provided by MDPI) as of 10.07.2021. The articles published until that date are archived at ceacr.archive.jams.pub by courtesy of JAMS.

Open Access
Abstract
CEACR 2020, 2(2), 15; doi: 10.35995/ceacr2010015

Osteogenesis Imperfecta-Related Osteoporosis: Between Low Bone Mineral Density and Multiple Fractures

Anda Dumitrașcu 1, * , Dan Nicolae Paduraru 2 , Ana Valea 3 , Mara Carsote 4
(this article belongs to the Special Issue ENDOPED International Congress 2020)
Received: 20 Oct 2020 / Accepted: 14 Nov 2020 / Published: 16 Nov 2020
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Abstract

Osteoporosis is reflected by low bone mineral density (BMD) at central Dual-Energy X-ray Absorptiometry (DXA) as well as clinical complications like low-trauma or spontaneous fractures. While typical primary osteoporosis is menopause-related, among the secondary causes of osteoporosis, osteogenesis imperfecta (OI) is listed for children, teenagers and adults. Underlining more than 17 mutations, and a heterogeneous clinical presentation, decreased BMD is associated with multiple fractures and impaired peak bone mass with lifelong effects.
Keywords: bone; fracture; osteoporosis; osteogenesis imperfect; skeleton
OPEN ACCESS
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).
CITE
Dumitrașcu, A.; Paduraru, D.N.; Valea, A.; Carsote, M. Osteogenesis Imperfecta-Related Osteoporosis: Between Low Bone Mineral Density and Multiple Fractures. CEACR 2020, 2, 15.
Dumitrașcu A, Paduraru DN, Valea A, Carsote M. Osteogenesis Imperfecta-Related Osteoporosis: Between Low Bone Mineral Density and Multiple Fractures. Central European Annals of Clinical Research. 2020; 2(2):15.
Dumitrașcu, Anda; Paduraru, Dan Nicolae; Valea, Ana; Carsote, Mara. 2020. "Osteogenesis Imperfecta-Related Osteoporosis: Between Low Bone Mineral Density and Multiple Fractures." CEACR 2, no. 2: 15.
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