TY  - EJOU
AU  - Dumitrașcu, D. Anda
AU  - Paduraru, P. Dan Nicolae
AU  - Valea, V. Ana
AU  - Carsote, C. Mara
TI  - Osteogenesis Imperfecta-Related Osteoporosis: Between Low Bone Mineral Density and Multiple Fractures
T2  - Central European Annals of Clinical Research

PY  - 2020
VL  - 2
IS  - 2
SN  - 2668-7305

AB  - Osteoporosis is reflected by low bone mineral density (BMD) at central Dual-Energy X-ray Absorptiometry (DXA) as well as clinical complications like low-trauma or spontaneous fractures. While typical primary osteoporosis is menopause-related, among the secondary causes of osteoporosis, osteogenesis imperfecta (OI) is listed for children, teenagers and adults. Underlining more than 17 mutations, and a heterogeneous clinical presentation, decreased BMD is associated with multiple fractures and impaired peak bone mass with lifelong effects.
KW  - bone
KW  - fracture
KW  - osteoporosis
KW  - osteogenesis imperfect
KW  - skeleton
DO  - 10.35995/ceacr2010015