@Article{ AUTHOR = {Dumitrașcu, Anda Dumitrașcu and Paduraru, Dan Nicolae Paduraru and Valea, Ana Valea and Carsote, Mara Carsote}, TITLE = {Osteogenesis Imperfecta-Related Osteoporosis: Between Low Bone Mineral Density and Multiple Fractures}, JOURNAL = {Central European Annals of Clinical Research}, VOLUME = {2}, YEAR = {2020}, NUMBER = {2}, PAGES = {0--0}, URL = {https://ceacr.archive.jams.pub/article/2/2/86}, ISSN = {2668-7305}, ABSTRACT = {Osteoporosis is reflected by low bone mineral density (BMD) at central Dual-Energy X-ray Absorptiometry (DXA) as well as clinical complications like low-trauma or spontaneous fractures. While typical primary osteoporosis is menopause-related, among the secondary causes of osteoporosis, osteogenesis imperfecta (OI) is listed for children, teenagers and adults. Underlining more than 17 mutations, and a heterogeneous clinical presentation, decreased BMD is associated with multiple fractures and impaired peak bone mass with lifelong effects.}, DOI = {10.35995/ceacr2010015} }